Analysis by Buzzword There was a poignant visualization of what science is really like rendered by Stanisław Lem (science fiction writer).  In a story, a strange machine created science; groups of people in white lab coats appearing to read and write papers, quarrel about them, burn them, shout and carrying them above their heads in … Continue reading Much Ado About Precision Medicine

Brain Model for Dummies I like to look at the brain from bottom up that is from neuronal health through synaptic health then I move my attention to networks (specific parts of brain), and network of local networks (the whole nine yards - your cognition).  Disruption can come at any level and upset the workings.  … Continue reading Current Approaches to Tackling Alzheimer Disease through Buzzwords (1)

it is indeed after July 25th, 2018 and that is when AVXL made claims that ANAVEX 2-73 should perform on average over period of a 1 years with following parameters Δ=+2 MMSE (+4.9 ADCS-ADL) starting from baselineof  >= 20 MMSE.  I do not exactly know how they got to that point but I take it as … Continue reading If ANAVEX 2-73 performs like this…savings are…!

Every time there is a news release the data provided is formated in different way and there are things omitted  so if somebody tries to get to the bottom of it he has to make assumptions.  I have the deep seated impression that he company strategically refrains from spilling the beans on ANAVEX 2-73.  It … Continue reading ANAVEX 2-73 after July 25th

I have plotted the data from CTAD 2017 presentation together with some linear extrapolation from the 57 week data and computed certain averages.  Once you do this you get the instantaneous insight into the data, it is amazing.  Here is the plot: From top are: 1. High Concentration Ascending (4 patients) 2. High Concentration Initially … Continue reading High Concentration Cohort Phase 2a Anavex 2-73 (continued)….

This analysis is just as bad as the rest of the stuff on this blog.  So let's start with percentages going to different types costs in producing a car as that of the MSRP price of ICE car (sticker price). Here it is... If we sum up the costs roughly attributed to generally manufacturing like … Continue reading Model 3, what it is worth to $TSLA

ANAVEX 2-73 Phase 2a trial has been discounted by some on the grounds that the sample size produced statistically insignificant results and that there was no placebo arm. Source of data for Natural Course of the Alzheimer Disease can be found in scientific literature and rudimentary comparative analysis can be made of vs. Phase 2a. … Continue reading ANAVEX 2-73 Phase 2a vs. Alzheimer’s Progress