Much Ado About Precision Medicine

Analysis by Buzzword There was a poignant visualization of what science is really like rendered by Stanisław Lem (science fiction writer).  In a story, a strange machine created science; groups of people in white lab coats appearing to read and write papers, quarrel about them, burn them, shout and carrying them above their heads in … Continue reading Much Ado About Precision Medicine

Current Approaches to Tackling Alzheimer Disease through Buzzwords (1)

Brain Model for Dummies I like to look at the brain from bottom up that is from neuronal health through synaptic health then I move my attention to networks (specific parts of brain), and network of local networks (the whole nine yards - your cognition).  Disruption can come at any level and upset the workings.  … Continue reading Current Approaches to Tackling Alzheimer Disease through Buzzwords (1)

High Concentration Cohort Phase 2a Anavex 2-73 (continued)….

I have plotted the data from CTAD 2017 presentation together with some linear extrapolation from the 57 week data and computed certain averages.  Once you do this you get the instantaneous insight into the data, it is amazing.  Here is the plot: From top are: 1. High Concentration Ascending (4 patients) 2. High Concentration Initially … Continue reading High Concentration Cohort Phase 2a Anavex 2-73 (continued)….

ANAVEX 2-73 Phase 2a vs. Alzheimer’s Progress

ANAVEX 2-73 Phase 2a trial has been discounted by some on the grounds that the sample size produced statistically insignificant results and that there was no placebo arm. Source of data for Natural Course of the Alzheimer Disease can be found in scientific literature and rudimentary comparative analysis can be made of vs. Phase 2a. … Continue reading ANAVEX 2-73 Phase 2a vs. Alzheimer’s Progress