Data on Parkinson's MDS-UPDRS Measure from $ANVS. There are 4 parts to this test. Part 1 deals general mood. From the slide it is obvious that there is improvemnt in the placebo like the dosed cohort; conclusion strong placebo effect. The difference is large as it is about 9%. Part 2 is asking patients for … Continue reading A Bit About MDS-UPDRS $AVXL $ANVS
Month: July 2021
ANNOVIS BIO, Mirror Mirror on the Wall…. $ANVS $AVXL $SAVA
How good are results from 25 days exploratory trial in Alzheimer's and Parkinson's? For those accustomed to measure of dementia in MMSE (Mini Mental State Examination) it comes as a shock that the actual Posiphen score are lower than placebo in MMSE. This is due to two unrelated facts. FACT 1: MMSE is notoriously insensitive … Continue reading ANNOVIS BIO, Mirror Mirror on the Wall…. $ANVS $AVXL $SAVA
How to Digest Alzheimer’s Data from AAIC 2021 $AVXL $ANVS $CRTX $SAVA
Stock Markets Reaction Is ........ There are two very basic reactions from stock market participants. A kee-jerk one where everybody buys in the rush of enthusiasm and damned be the price. "I just want to get hold of it at any price". And the measured one where the price and acquisition are weighted against each … Continue reading How to Digest Alzheimer’s Data from AAIC 2021 $AVXL $ANVS $CRTX $SAVA
AAIC 2021 as Viewed Through My Prism of Expectations $SAVA $CRTX $ATHA $AVXL
Monday 10:00 AM Eastern Time $SAVA Poster: “SavaDx, a Novel Plasma Biomarker to Detect Alzheimer’s Disease, Confirms Mechanism of Action of Simufilam” Sounds like more of "curing Alzheimer's with biomarker" or the best left for Thursday? Is there a change in narrative towards proteopathy? Proteopathy - Sickness of the protein making machinery. A bow in … Continue reading AAIC 2021 as Viewed Through My Prism of Expectations $SAVA $CRTX $ATHA $AVXL
Why Blarcamesine Might Be Working Against P. gingivalis $CRTX $AVXL $ANVS $SAVA
I have been directed by the author to an article about $CRTX and the evidence that Alzheimer's might be caused by virulence of the bacterium P. gingivalis. The bacterium can hitch a ride from the mouth on cells of the immune systen and enter the brain through the Brain Blood Barrier. Then it slowely makes … Continue reading Why Blarcamesine Might Be Working Against P. gingivalis $CRTX $AVXL $ANVS $SAVA
Alzheimer’s, Due to Fatal Infection? Cortexyme vs. Annovis Bio $CRTX $ANVS
The question is a simple one. Is Alzheimer's a disease or a syndrome?. If it is a disease then it shall have one particular etiology with one drug to it. Of course, this is a great exaggeration but serves its purpose of illustration the difference between a disease and a syndrome, which is a set of symptoms that can have varied etiology. Talking more in terms of game theory, investing in Alzheimer's drugs can be zero sum game or game where many are going to be winners, although fractionally
AAIC 2021 July 26-30 $SAVA $ANVS $AVXL
Etiology Wars The Aduhelm fiasco brings about the realization that it certainly isn't a A-beta the reason for the dementia of Azheimer's. The press still touts its sister the tau tangles. This narrative now goes through trasformation into the story of neuroinflammation with which are bound the two above-listed companies $SAVA and $ANVS. The transformation … Continue reading AAIC 2021 July 26-30 $SAVA $ANVS $AVXL