Month: October 2022

Donezepil, Simufilam And Blarcamesine Performance Compared As Much As It Is Possible. $SAVA $AVXL

~ Piotr Pietrzkiewicz ~ Leave a comment

It was suggested to me to comparing the hypothetical performance of Blarcamesine in phase 2b/3 to Donezepil. Hat Tip to @Trainguy1. I tried to compare the 3 drugs, including 9 months performnace of Simufilam, to Donezepil as it was formated or presented in Fig. 2 on Donezepil Label coming with the drug, and FDA approved. … Continue reading Donezepil, Simufilam And Blarcamesine Performance Compared As Much As It Is Possible. $SAVA $AVXL

In Search of Therapeutic Effect Patterns In Simufilam, Blarcamesine and Approximation of Placebo. $SAVA $AVXL

~ Piotr Pietrzkiewicz ~ 1 Comment

Plotting Δ ΜΜSE or Δ ADAS-Cog11 or Just Changes in Cognition for Each Patient I came with an idea to plot in a given trial all the cognition changes from the highest score to the lowest. On a spreadsheet I arranged patients in this order with their corressponding cognition deltas scores. When you see a … Continue reading In Search of Therapeutic Effect Patterns In Simufilam, Blarcamesine and Approximation of Placebo. $SAVA $AVXL

Comparing Apples To Oranges, Or Rather The Hypotetical Performance Of Blarcamesine And Simufilam. $AVXL vs. $SAVA

~ Piotr Pietrzkiewicz ~ Leave a comment

This is quick and dirty, I have no time for bibliography and references. I had been giving references links but now I have no time so if you want references I can provided them on request. For most of you the references for those illustrations are already known. I apologize for misspellings and gramatical errors. … Continue reading Comparing Apples To Oranges, Or Rather The Hypotetical Performance Of Blarcamesine And Simufilam. $AVXL vs. $SAVA

Change Of Language On ClinicalTrials.Gov Page For Blarcamesine Phase 2b/3 Alzheimer’s Trial. $AVXL

~ Piotr Pietrzkiewicz ~ Leave a comment

You can devine the future from coffee grinds as well as from the language change... But only if you don't know much about the implications of language in phase 2b/3 for Blarcamesine for Alzheimer's. Mr. Brodkin has published this tweet. Link: https://twitter.com/jesse_brodkin/status/1550477966123171840?s=20&t=MdTQ5Aes7PJyFbCFHRQQAQ One of the points he makes is that Anavex has changed the wording … Continue reading Change Of Language On ClinicalTrials.Gov Page For Blarcamesine Phase 2b/3 Alzheimer’s Trial. $AVXL